Cognitive disturbances
in patients with tics and Tourette's syndrome and their correction with
pyritinol
[Article in Russian]
Zykov VP, Begasheva OI.
Zh Nevrol Psikhiatr Im SS Korsakova. 2003;103(11):10-4
ABSTRACT
Ninety-four patients with tick hyperkinesis (57) and
Tourette's syndrome (37) were studied. Neuropsychological examination revealed
memory, attention and audio-motor disturbances and symptoms of dysgraphia and
dyslexia. Cognitive impairment may develop before ticks appearance and
aggravate during hyperkinesis exacerbation. In the patients with Tourette's
syndrome, cortical dysfunctions were mostly pronounced. These cognitive
disturbances correlated with the indices of spectral analysis of bioelectrical
brain activity in frontal and temporal areas. In 83 patients, an efficacy of
pyritinol treatment combined with basic therapy was studied. Pyritinol
given in dosage 200-300 mg daily to patients aged 5-7 years and 600 mg--to
those aged over 7 years during 6 weeks significantly improved memory,
attention and praxis function.
Galantamine
| Idebenone | Vinpocetine
| benfotiamine
|
Memantine
Deprenyl | Piracetam | Picamilon
| CDP Choline |
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